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CBD + Science in the News

CBD + Science in the News

The pre-print paper Cannabidiol Inhibits SARS-CoV-2 Replication and Promotes the Host Innate Immune Response dropped into the news cycle this week. Of course, as a CBD company founder, I have something to say about it. That something can be summarized most concisely as "Woah Woah Woah, let's take it slow, baby."

Keeping it real in the CBD space

Reading papers may be the most elegant expression of my deep-seated nerdism, and I do it a lot in this field. And if there is one thing I know, it is to use caution when reading a pre-print paper. All academic papers need to run the gauntlet—they call it peer review—before a paper is published. That includes an often lengthy process in which fellow scientists and academics attempt to poke holes in how the experiments were designed and performed and if the data is being interpreted correctly, among other methodological checkpoints.

In this case, the paper's summary is as follows:

The rapid spread of COVID-19 underscores the need for new treatments. Here we report that cannabidiol (CBD), a compound produced by the cannabis plant, inhibits SARS-CoV-2 infection. CBD and its metabolite, 7-OH-CBD, but not congeneric cannabinoids, potently block SARS-CoV-2 replication in lung epithelial cells. CBD acts after cellular infection, inhibiting viral gene expression and reversing many effects of SARS-CoV-2 on host gene transcription. CBD induces interferon expression and up-regulates its antiviral signaling pathway. A cohort of human patients previously taking CBD had significantly lower SARSCoV-2 infection incidence of up to an order of magnitude relative to matched pairs or the general population. This study highlights CBD, and its active metabolite, 7-OH-CBD, as potential preventative agents and therapeutic treatments for SARS-CoV-2 at early stages of infection.

What's next?

Sounds really exciting, I know! Studying if "CBD really works" on a variety of ailments is a relatively new field due to cannabis' legal standing at the federal level, and so while this study and so many others are utterly thrilling in so many ways, please use caution when making important decisions about you and your family's wellness. Because we love you, and we want you to be happy and healthy.  xoxo